AN UNBIASED VIEW OF PALMITOYLETHANOLAMIDE

2015). These experiments, taken with each other, advise that, Whilst a direct activation of GPR55 or PPAR‐α occurs, PEA can deliver its anti‐inflammatory motion in the intestine also by using indirect activation of CB1 and CB2 receptors, most likely due to the ability of this compound to potentiate the motion of endocannabinoids at these recep